Replicating a GWAS: two novel candidate markers for oligospermia in Greek population

Genome-wide association studies have paved the way for the discovery of new markers regarding many diseases, including male infertility. A previous study on Caucasians highlighted 172 polymorphisms for their putative association with male infertility and we attempted to replicate these findings on our dataset comprising of Greek male individuals (n = 360). We retrieved 59 out of […]

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What leads the spermatozoa towards the egg?

Spermatogenesis is one of the most complex processes in humans, involving many genes and even more signaling pathways. After the process of spermatogenesis is completed, the newly produced spermatozoa must travel a relatively long distance in order to be able to fertilize the egg. But how exactly do the spermatozoa know the right direction?  It […]

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Healthy sperm and lifestyle

It is now widely known how much fertility and its disorders affect couples around the world. But is it easy to maintain sperm health?Researchers at the Mayo clinic conducted a research that focused firstly on what affects and alters sperm quality and subsequently, ways to improve its quality.More specifically, it is essential for every man […]

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What does TERATOSPERMIA mean

What does TERATOSPERMIA mean?What does ASTHENOSPERMIA mean?What does OLIGOSPERMIA mean?What does AZOOSPERMIA mean?What does NORMOSPERMIA mean? The above definitions may sound scary, but they are nothing more than sperm conditions. More specifically, a large percentage of men have been tested for their sperm quality in their lifetime. The seminogram, the test that gives us specific […]

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Male fertility and COVID-19

COVID-19 is now a worldwide emergency as it has affected millions of people. But what about the reproductive potential of males that have undergone COVID-19 infection? It is known that the virus’ entrance to the human body is through the ACE2 receptors, a molecule that is found to be enriched in testis and more specifically […]

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